Penny for your thoughts campaign

Penny for your thoughts campaign Penny for your thoughts campaign Penny for your thoughts campaign

Penny for your thoughts campaign

Penny for your thoughts campaign Penny for your thoughts campaign Penny for your thoughts campaign
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    • Home
    • What is the Vaccine?
    • GoFundMe
    • New RVX data
    • Articles and Info
    • Campaign Advocates
    • Dr. Halford's Research
    • Contact Us
    • Para español
    • GoFundMe Español
    • Petition Español
  • Home
  • What is the Vaccine?
  • GoFundMe
  • New RVX data
  • Articles and Info
  • Campaign Advocates
  • Dr. Halford's Research
  • Contact Us
  • Para español
  • GoFundMe Español
  • Petition Español

New Rational Vaccines Data

Journal of Virology publishes paper on Rational Vaccines live-attenuated vaccine candidate

The major finding of the study, "Herpes Simplex Virus 1 (HSV-1) 0ΔNLS Live-Attenuated Vaccine Protects against Ocular HSV-1 Infection in the Absence of Neutralizing Antibody in HSV-1 gB T Cell Receptor-Specific Transgenic Mice," found that the company's RVX101 vaccine candidate used to immunize a unique mouse line was shown to provide highly protective immunity and prevent herpes-associated neovascularization. 

Link

Distinguishing Features of High- and Low-Dose Vaccine against Ocular HSV-1 Infection

The protective efficacy of a live-attenuated HSV type 1 (HSV-1) vaccine, HSV-1 was evaluated in mice prophylactically in response to ocular HSV-1 challenge. Mice vaccinated with the HSV-1 0ΔNLS were found to be more resistant to subsequent ocular virus

Link

Assessment of Two Novel Live-Attenuated Vaccine Candidates for Herpes Simplex Virus 2 (HSV-2)

In summary, RVx201 appears to be safe in guinea pigs, as it did not produce observable signs of disease, did not establish detectable latency, and did not produce recurrences. RVx202 produced minor injection site inflammation, viral shedding in vaginal secretions at early time points following vaginal inoculation (but not following intradermal inoculation) but did not establish detectable latency or produce recurrences.

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